Is Collagenase
Worth the Expense and the Risks?

last updated November 21, 2022
2:34 pm

Collagenase clostridium histolyticum is the newest form of this enzyme that is used to treat Peyronies disease. It is the only FDA approved injection of this type. And, it is marketed under the trade name of XIAFLEX®.

More Success Than Most

collagenase injections for peyronies disease treatments

This form of collagenase has had more success in straightening a bent penis caused by Peyronies disease than the other injectables. However, the results, though decent, are still not spectacular.

Don't expect to get arrow straight erections after you've spent $30,000 to use it. Yes, thirty thousand dollars is the estimated cost for a full set of these collagenase injections.

The trials show that with certain types of cases you can expect up to 35% improvement in the bend.

I know 35% doesn't sound like a lot. But, it can be enough to make intercourse possible again, and, painless again.

Is Collagenase Used?

The procedure for using Collagenase is very simple.

Collagenase is a prescription drug, administered through injection, directly into the Peyronies scar by a medical doctor.

collagenase injections for Peyronies disease

The collagenase liquid is injected as the needle is withdrawn or moved around in the area while the fluid is being injected.

The injection is done this way to cover the most possible scar/plaque area with the enzyme.

It is supposed to dissolve the scar/plaque. Good in theory. Somewhat lame in actual results.

And: If you have calcification in the scar/plaque formation(s), it has shown to be ineffective.

What Is The Cost?

As we mentioned above, It’s HUGE!

The program is four cycles of two injections each.

The cost for this Collagenase treatment is estimated to be $3,300 per injection. Per injection! That translates to a whopping $26,000 for the entire treatment.

PLUS: physician’s fees (Approx $1,200 - $3,000). Please click the link directly above. That is no error and no joke.

And, to us, that just sounds like a stupid lot of money for minimal results.

Do We Really Need Drugs
Avoid Penis Surgery?

Drugs are not the answer to every human problem.

Drugs can be miraculous at certain times and in certain circumstances.

For example, a doctor friend of mine, Dr. Alex Lesuk, (whose father suffered a very serious heart attack) spent his life discovering a serum that dissolves blood clots in the heart almost immediately. He became quite famous for this about 50 years ago. Nice! huh?

His serum has saved many lives.

There are many other wonderful drugs like simple morphine for intense pain, etc...

But, drugs are not the best answer for everything.

And, they have proven not to be the most effective answer for straightening a bent penis.

Worse: Drugs always have some kind of side effect(s). And, sometimes some serious possible side effects. You can read about those for XIAFLEX® at their official website.

And, here’s the message in this article:

Why Risk the Unnecessary Side Effects
A Treatment That Has Proven To Be
Only Moderately Effective?

You see, not only is this drug used on Peyronies only moderately effective for straightening this condition, it also come with some really unpleasant and serious possible side effects.

Let’s take a look at what some of the possible side effects of using these injections are:

 -  “The most common (≥25%) adverse reactions reported in patients treated with collagenase clostridium histolyticum, and at an incidence greater than in patients receiving placebo, were penile hematoma, penile swelling, and penile pain

ref: Xiaflex (collagenase clostridium histolyticum) for injection [prescribing information]. Chesterbrook, PA: Auxilium Pharmaceuticals, Inc; December 2013.

 -  “After treatment, blood vessels in your penis may also break, causing blood to collect under the skin (hematoma). This could require a procedure to drain the blood from under the skin.”


  •  Penile fracture (talk about going from bad to worse!)

  •  Breathing trouble

  •  Chest pain

  •  Allergic reactions (because the injectible contains foreign proteins)

  •  Hives

  •  Pain during sex

  •  Erectile dysfunction

  •  Penile itching

  •  Itchy scrotum

  •  Decreased interest in sex

  •  Loss in sexual ability, performance, drive

 -  Great so far??

Please, you don't just have to take our word for this. Here is: the more complete list of possible side effects from the manufacturer of  collagenase clostridium histolyticum used for Peyronies disease.

Do you really want to risk all of that?

Especially when you can only expect moderate results at best?

And, it’s going to cost you about $28,000?


What’s The Point?

So, here's our point:

Collagenase is not a truly effect treatment for Peyronies disease straightening. For straightening, collagenase clostridium histolyticum has shown to give only moderate results at best. Even if you are one of the lucky ones. And , it comes with a whole lot of possible unpleasant side effects.

So, why use it when there is a much better way?

You won’t have to risk any of those awful side effects.

AND: You can usually get far superior results, in a safer way, for under $300. Yes, $30,000 vs $300.

Both methods are medically endorsed and recommended. Both methods are FDA approved.

The clinically proven
Safest and Most Effective method
straightening a bending or curving erection
simple correct penis traction.

collagenase injections or penis traction therapy for peyronies disease

Correct penis traction is so good that it is now medically endorsed and recommended in 29 countries worldwide.

This includes:

USA • Canada • United Kingdom • France • Belgium • Holland • Germany • Denmark • Brazil • Thailand • Sweden • Taiwan • Uruguay •  Switzerland • Portugal • Japan • Argentina • Philippines • Serbia • Venezuela • Italy• Luxembourg • Australia • Andorra • Mexico • Chile • Malaysia • Tunisia • Norway

Under $300

"William, I thought you just said $26,000 plus physician’s fees."

I did. That’s the reported cost for using FDA approved XIAFLEX® collagenase clostridium histolyticum. (there is no generic brand at this time).

I also told you that the reports say if it works for you, it is only about 35% effective at best and only for certain men.

Yes, bummer. Right?

NOW: What if you could save about $28,000 and get:

  • Great Results
  • Guaranteed Results
  • None of those potential unpleasant and serious side effects
  • Spend under $300
  • Use the method that has been clinically proven Safest and Most Effective
  • Use a method that is Medically Endorsed and Recommended in 29 countries worldwide (including the USA)

Doesn't it make sense to try that method first?

The Method Clinically Proven
Safest and Most Effective

OK. If you’ve come this far, you are ready to hear about correct penis traction. The Safest and Most Effective medically endorsed method for straightening a bent penis.

You'll learn:  Why it works.

And:  Why it has proven to be so good.

Penis Traction Therapy

Why inject yourself with all kinds of chemicals for a huge cost when all you have to do is stretch this scar out. Yes, all Penis Traction Therapy (PTT) comes down to is Safe Effective Controlled penis stretching.

It is really that plain and simple.

Stretch out the scar(s) and plaque and your erections will straighten out.

penis traction therapy
how penis traction therapy works

That’s it!

So easy.

So inexpensive.

So true!

Does that seem too simple?

Do we have to be more complicated, more expensive, and take unnecessary risks to get straightened?


Doing It Yourself?

Once you grasp the concept of stretching out the short hard tissue, you think you could probably do it by yourself with just your own hands at no cost.


But, doing it by hand can cause injury or bending in yet another direction unless you really know what you are doing. How many of us do? How many of us have the patience and time that requires every day, also?

Correct penis traction, however: is safe, gentle, and effective. And, it’s so inexpensive that it doesn’t make sense not to do it correctly.

Correct PTT is also something you do by yourself in complete privacy. It's easy, and, your actual effort is under 2 minutes a day. Putting the device on (under a minute), and, taking it off (under 15 seconds).

Correct traction results in nice even results because the unit pulls the scar/plaque correctly in a scientifically measured, balanced, even way.

You just have to make sure you use a high quality traction device. And, use it correctly.

Use Only The Best

This is the hard part.


There are a lot of cheap knock off, imitator’s devices out there that could injure you and/or damage your penis.

The reason there are many cheaply made devices is, correct traction is so effective that you can actually enlarge your penis with traction. Yes, make it bigger. Permanently. They call it "Male Enhancement". We used to just call it a bigger dick. Oh, politically correctness....

Now, are you getting ahead of us here? That’s right... Who do you think buys most of these units?

Men with Peyronies Disease? Or, young men with a small amount of money and a lot of sexual insecurity?

Make sense?

But, for under $300 you can have one of the best built units in the entire world.

So don’t scrimp here. Don't go for the poorly made $100 ones. You just saved $28,000 on a treatment that has proven only moderatley effective. Get the very best unit possible.

When handling my own Peyronies bending problem, I found only two manufacturers of penis traction devices that met all of my own personal requirements for Safety and Effectiveness.

The Results Are Guaranteed

Remember when most things came with a guarantee?

What do you think the guarantee with collagenase is? Correct. Nothing. No guarantee at all.

What is the guarantee with Penis Traction Therapy?

Well, if you decided to try either of the two units we found best, you get a six month guarantee that basically says: If you don’t like the results you’re getting in the first six months you can return the unit for a full refund.

Doesn’t it at least make sense to try correct traction before spending a small fortune on something like collagenase? Or, a dangerous surgery? (the only other medically recommended methods that have proven reliable)

Enjoying Your Success

straighten a bent penis without surgery

Now, on the other hand, when you see your penis straightening with correct traction and you realize you just saved yourself $28,000 on injections, here’s what I suggest you do:

Take some of that $28,000 you just saved on collagenase injections and buy you and your wife something nice. Even something small. You deserve it.

After all, isn’t that why you worked so hard for your money?

Be Well.....

~ William

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